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Article

Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells.

PLoS computational biology - 16 Dec 2010

Markowetz Florian, Mulder Klaas W, Airoldi Edoardo M, Lemischka Ihor R, Troyanskaya Olga G

Abstract excerpt

Embryonic stem cells (ESC) have the potential to self-renew indefinitely and to differentiate into any of the three germ layers. The molecular mechanisms for self-renewal, maintenance of pluripotency and lineage specification are poorly understood, but recent results point to a key role for epige...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21187909
DOI: 10.1371/journal.pcbi.1001034
PMCID: PMC3002996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21187909-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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