Article
Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation.
Journal of cellular physiology - 1 Jun 2009
Krejcí Jana, Uhlírová Radka, Galiová Gabriela, Kozubek Stanislav, Smigová Jana, Bártová Eva
Abstract excerpt
Epigenetic marks are important factors regulating the pluripotency and differentiation of human embryonic stem cells (hESCs). In this study, we analyzed H3K9 acetylation, an epigenetic mark associated with transcriptionally active chromatin, during endoderm-like differentiation of hESCs. ChIP-on-...
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