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Article

Homologous Recombination in Hybridoma Cells: Dependence on Time and Fragment Length

1 Sept 1990

Abstract excerpt

Mutant hybridoma-myeloma cell lines that are defective in immunoglobulin production are expected to be useful for defining the molecular requirements of immunoglobulin gene expression. The analysis of such mutants would be greatly facilitated if they could be mapped by marker rescue, i.e., by identifying the segments of wild-type DNA that can restore the normal phenotype by homologous recombination with the...

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PMID: 2117699
DOI: 10.1128/mcb.10.9.4466-4472.1990

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Homologous Recombination in Hybridoma Cells: Dependence on Time and Fragment LengthPMID 2117699Read ↗

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