Article
Scid mouse Pre-B cells with intracellular mu chains: analysis of recombinase activity and IgH gene rearrangements.
International immunology - 1 Apr 1993
Kotloff D B, Bosma M J, Ruetsch N R
Abstract excerpt
Four Pre-B cell clones with intracellular mu chains were recovered from individual leaky scid mice by transformation of bone marrow or peritoneal cells with Abelson murine leukemia virus. Three clones were derived from independent bone marrow cell cultures. These express the defective scid recomb...
Topics
- Alleles
- Animals
- B-Lymphocytes
- Base Sequence
- Cell Line
- DNA
- DNA Nucleotidyltransferases
- Female
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Genes, Immunoglobulin
- Hematopoietic Stem Cells
- Immunoglobulin mu-Chains
- Integrases
- Mice
- Mice, SCID
- Molecular Sequence Data
- Recombinases