Article
Isolation of new nonsense and frameshift mutants in the immunoglobulin mu heavy-chain gene of hybridoma cells.
Somatic cell and molecular genetics - 1 Jul 1993
Connor A, Collins C, Jiang L, McMaster M, Shulman M J
Abstract excerpt
In order to expand the experimental material available for genetic and biochemical analyses of the natural immunoglobulin genes, we have isolated a variety of mutant mouse hybridoma cell lines. Some of these mutants have partial or complete deletions of the mu gene. Other mutants have nonsense or...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Primers
- Exons
- Frameshift Mutation
- Genotype
- Hybridomas
- Immunoglobulin M
- Immunoglobulin Variable Region
- Immunoglobulin mu-Chains
- Mice
- Molecular Sequence Data
- Phenotype
- Picrates
- Restriction Mapping