Article
Isolation of new nonsense and frameshift mutants in the immunoglobulin mu heavy-chain gene of hybridoma cells.
Somatic cell and molecular genetics - 1 Jul 1993
Connor A, Collins C, Jiang L, McMaster M, Shulman M J
Abstract excerpt
In order to expand the experimental material available for genetic and biochemical analyses of the natural immunoglobulin genes, we have isolated a variety of mutant mouse hybridoma cell lines. Some of these mutants have partial or complete deletions of the mu gene. Other mutants have nonsense or frameshift mutations in the exons encoding the variable and the second and third constant region domains of the mu...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.