Article
Increased cytotoxicity of ricin in a putative Golgi-defective mutant of Chinese hamster ovary cell.
Experimental cell research - 1 Sept 1990
Yoshida T, Chen C H, Zhang M S, Wu H C
Abstract excerpt
We have studied the cytotoxicity of ricin in a monensin-resistant mutant (MonR-31) of Chinese hamster ovary (CHO) cell line which is presumably altered in Golgi functions/structures. The cytotoxicity of ricin was increased in MonR-31 mutant cells compared with that in its parental CHO cells. In wild-type CHO cells, the cytotoxicity of ricin was enhanced by HN4Cl, bafilomycin A1, or nigericin. The enhancement of...
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