Article
Increased cytotoxicity of ricin in a putative Golgi-defective mutant of Chinese hamster ovary cell.
Experimental cell research - 1 Sept 1990
Yoshida T, Chen C H, Zhang M S, Wu H C
Abstract excerpt
We have studied the cytotoxicity of ricin in a monensin-resistant mutant (MonR-31) of Chinese hamster ovary (CHO) cell line which is presumably altered in Golgi functions/structures. The cytotoxicity of ricin was increased in MonR-31 mutant cells compared with that in its parental CHO cells. In w...
Topics
- Alkaloids
- Ammonium Chloride
- Animals
- Anti-Bacterial Agents
- Brefeldin A
- Cell Line
- Cyclopentanes
- Diphtheria Toxin
- Glycosylation
- Golgi Apparatus
- Lectins
- Macrolides
- Mutation
- Nigericin
- Plant Lectins
- Protein Biosynthesis
- Ribosome Inactivating Proteins, Type 2
- Ricin