Article
Isolation of Chinese hamster ovary ribosomal mutants differentially resistant to ricin, abrin, and modeccin.
The Journal of biological chemistry - 5 Jan 1990
Sallustio S, Stanley P
Abstract excerpt
The molecular action of ricin A chain involves cleavage of the N-glycosidic bond between ribose and the adenine 4324 nucleotides from the 5' end of mammalian 28 S rRNA (Endo, Y., and Tsurugi, K. (1987) J. Biol. Chem. 262, 8128-8130). In this paper, four ricin- and abrin-resistant Chinese hamster...
Topics
- Abrin
- Adenine
- Animals
- Cell Line
- Cricetinae
- Drug Resistance
- Female
- Lectins
- Mutation
- Ovary
- Plant Lectins
- Plant Proteins
- Protein Synthesis Inhibitors
- RNA, Ribosomal, 28S
- Ribose
- Ribosomal Proteins
- Ribosome Inactivating Proteins, Type 2
- Ribosomes
