Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation of Chinese hamster ovary ribosomal mutants differentially resistant to ricin, abrin, and modeccin.

The Journal of biological chemistry - 5 Jan 1990

Sallustio S, Stanley P

Abstract excerpt

The molecular action of ricin A chain involves cleavage of the N-glycosidic bond between ribose and the adenine 4324 nucleotides from the 5' end of mammalian 28 S rRNA (Endo, Y., and Tsurugi, K. (1987) J. Biol. Chem. 262, 8128-8130). In this paper, four ricin- and abrin-resistant Chinese hamster ovary cell mutants that possess ribosomes resistant to this N-glycosidase action are described. Three of the mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Cricetinae
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Plant Proteins

Share to Ribosomal Proteins

Share to Ribosomes

Source

Identifiers

PMID: 2104622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation of Chinese hamster ovary ribosomal mutants differentially resistant to ricin, abrin, and modeccin.PMID 2104622Read ↗

Lectin-resistant CHO cells: selection of seven new mutants resistant to ricin.Semantic proximity Read ↗

A class of mutant CHO cells resistant to cholera toxin rapidly degrades the catalytic polypeptide of cholera toxin and exhibits increased endoplasmic reticulum-associated degradation.Semantic proximity Read ↗

An N-terminal fragment of yeast ribosomal protein L3 inhibits the cytotoxicity of pokeweed antiviral protein in Saccharomyces cerevisiae.Semantic proximity Read ↗

Expression and functional properties of genetically engineered ricin B chain lacking galactose-binding activity.Semantic proximity Read ↗

Inhibition of endoplasmic reticulum-associated degradation in CHO cells resistant to cholera toxin, Pseudomonas aeruginosa exotoxin A, and ricin.Semantic proximity Read ↗

Ricin inhibits activation of the unfolded protein response by preventing splicing of the HAC1 mRNA.Semantic proximity Read ↗

Characterization of prokaryotic recombinant Aspergillus ribotoxin alpha-sarcin.Semantic proximity Read ↗

Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol.Semantic proximity Read ↗

Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast.Semantic proximity Read ↗

Double-site ricin B chain mutants retain galactose binding.Semantic proximity Read ↗

Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits.Semantic proximity Read ↗

Catalytic and cytotoxic activities of recombinant ricin A chain mutants with charged residues added at the carboxyl terminus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.