Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus.

The Journal of cell biology - 9 Feb 1998

Llorente A, Rapak A, Schmid S L, van Deurs B, Sandvig K

Abstract excerpt

Endocytosis and intracellular transport of ricin were studied in stable transfected HeLa cells where overexpression of wild-type (WT) or mutant dynamin is regulated by tetracycline. Overexpression of the temperature-sensitive mutant dynG273D at the nonpermissive temperature or the dynK44A mutant inhibits clathrin-dependent endocytosis (Damke, H., T. Baba, A.M. van der Blieck, and S.L. Schmid. 1995. J. Cell Biol....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cell Division
Share to Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Golgi Apparatus

Share to GTP Phosphohydrolases

Share to HeLa Cells

Share to Mutation

Share to Protein Biosynthesis

Source

Open in PubMed Open full text

Identifiers

PMID: 9456316
DOI: 10.1083/jcb.140.3.553
PMCID: PMC2140157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus.PMID 9456316Read ↗

Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex.Semantic proximity Read ↗

Ebulin l Is Internalized in Cells by Both Clathrin-Dependent and -Independent Mechanisms and Does Not Require Clathrin or Dynamin for Intoxication.Semantic proximity Read ↗

Dynamin-dependent transferrin receptor recycling by endosome-derived clathrin-coated vesicles.Semantic proximity Read ↗

Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol.Semantic proximity Read ↗

Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment.Semantic proximity Read ↗

Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor.Semantic proximity Read ↗

Disruption of Golgi markers by two RILP-directed shRNAs in neurons: A new role for RILP or a neuron-specific off-target phenotype?Semantic proximity Read ↗

Src kinase regulates the integrity and function of the Golgi apparatus via activation of dynamin 2.Semantic proximity Read ↗

“Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?”Semantic proximity Read ↗

Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol.Semantic proximity Read ↗

Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism.Semantic proximity Read ↗

Modulation of Rac localization and function by dynamin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.