Article
Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction.
The Journal of biological chemistry - 11 Mar 2011
Maillard Pierre V, Zoete Vincent, Michielin Olivier, Trono Didier
Abstract excerpt
The tropism of retroviruses relies on their ability to exploit cellular factors for their replication as well as to avoid host-encoded inhibitory activities such as TRIM5α. N-tropic murine leukemia virus is sensitive to human TRIM5α (huTRIM5α) restriction, whereas human immunodeficiency virus typ...
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