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Capsid-binding retrovirus restriction factors: discovery, restriction specificity and implications for the development of novel therapeutics

12 Sept 2013

Abstract excerpt

The development of drugs against human immunodeficiency virus type 1 infection has been highly successful, and numerous combinational treatments are currently available. However, the risk of the emergence of resistance and the toxic effects associated with prolonged use of antiretroviral therapies have emphasized the need to consider alternative approaches. One possible area of investigation is provided by the...

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PMID: 24026671
DOI: 10.1099/vir.0.058180-0

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