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Article

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding.

Virology - 15 Sept 2006

Javanbakht Hassan, Yuan Wen, Yeung Darwin F, Song Byeongwoon, Diaz-Griffero Felipe, Li Yuan, Li Xing, Stremlau Matthew, Sodroski Joseph

Abstract excerpt

The coiled-coil domain of the tripartite motif (TRIM) family protein TRIM5alpha is required for trimerization and function as an antiretroviral restriction factor. Unlike the coiled-coil regions of other related TRIM proteins, the coiled coil of TRIM5alpha is not sufficient for multimerization. T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16808955
DOI: 10.1016/j.virol.2006.05.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16808955-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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