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Article

Common variants in NOD2 and IL23R are not associated with inflammatory bowel disease in Indians.

Journal of gastroenterology and hepatology - 1 Apr 2011

Mahurkar Swapna, Banerjee Rupa, Rani Vasantha S, Thakur Nikita, Rao Guduru Venkat, Reddy Duvvuru Nageshwar, Chandak Giriraj R

Abstract excerpt

BACKGROUND AND AIM: Ulcerative colitis (UC) and Crohn's disease (CD) are two major phenotypes of inflammatory bowel disease (IBD) that present with inflammation of the colon or the entire gastrointestinal tract, respectively. Genome-wide association studies have confirmed the role of nucleotide-binding oligomerization domain protein-2 (NOD2) variants and identified several other genes associated with IBD. We...

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Source

Identifiers

PMID: 21155887
DOI: 10.1111/j.1440-1746.2010.06533.x

Genes

NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variants in NOD2 and IL23R are not associated with inflammatory bowel disease in Indians.PMID 21155887Read ↗

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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.Semantic proximity Read ↗

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease.Semantic proximity Read ↗

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Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.Semantic proximity Read ↗

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.Semantic proximity Read ↗

NOD2 gene mutations associate weakly with ulcerative colitis but not with Crohn's disease in Indian patients with inflammatory bowel disease.Semantic proximity Read ↗

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