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Article

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.

PloS one - 30 Dec 2010

Glas Jürgen, Seiderer Julia, Tillack Cornelia, Pfennig Simone, Beigel Florian, Jürgens Matthias, Olszak Torsten, Laubender Rüdiger P, Weidinger Maria, Müller-Myhsok Bertram, Göke Burkhard, Ochsenkühn Thomas, Lohse Peter, Diegelmann Julia, Czamara Darina, Brand Stephan

Abstract excerpt

BACKGROUND: The aims were to analyze two novel NOD2 variants (rs2066843 and rs2076756) in a large cohort of patients with inflammatory bowel disease and to elucidate phenotypic consequences. METHODOLOGY/PRINCIPAL FINDINGS: Genomic DNA from 2700 Caucasians including 812 patients with Crohn's disease (CD), 442 patients with ulcerative colitis (UC), and 1446 healthy controls was analyzed for the NOD2 SNPs rs2066843...

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Source

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Identifiers

PMID: 21209938
DOI: 10.1371/journal.pone.0014466
PMCID: PMC3012690

Genes

NOD2

Variants

rs2066843
rs2066844
rs2066847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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