Article
NOD2 gene mutations associate weakly with ulcerative colitis but not with Crohn's disease in Indian patients with inflammatory bowel disease.
Gene - 10 Jan 2013
Pugazhendhi Srinivasan, Santhanam Srikanth, Venkataraman Jayanthi, Creveaux Isabelle, Ramakrishna Balakrishnan S
Abstract excerpt
BACKGROUND: Three mutations (two missense and one frameshift) in the NOD2 gene are associated with Crohn's disease (CD) in a proportion of patients with Crohn's disease in North America, Europe and Australia. These three mutations are not found in Indian patients with CD. We undertook new studies to identify polymorphisms in the NOD2 gene in the Indian population and to detect whether any of these were associated...
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