Article
Increased fMRI signal with age in familial Alzheimer's disease mutation carriers.
Neurobiology of aging - 1 Feb 2012
Braskie Meredith N, Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel Angel, Cummings Jeffrey L, Bookheimer Susan Y, Ringman John M
Abstract excerpt
Although many Alzheimer's disease (AD) patients have a family history of the disease, it is rarely inherited in a predictable way. Functional magnetic resonance imaging (fMRI) studies of nondemented adults carrying familial AD mutations provide an opportunity to prospectively identify brain differences associated with early AD-related changes. We compared fMRI activity of 18 nondemented autosomal dominant AD...
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