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Article

Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Quiroz Yakeel T, Willment Kim Celone, Castrillon Gabriel, Muniz Martha, Lopera Francisco, Budson Andrew, Stern Chantal E

Abstract excerpt

BACKGROUND: Brain regions critical to episodic memory are altered during the preclinical stages of Alzheimer's disease (AD). However, reliable means of identifying cognitively-normal individuals at higher risk to develop AD have not been established. OBJECTIVE: To examine whether functional MRI can detect early functional changes associated with scene encoding in a group of presymptomatic presenilin-1 (PSEN1)...

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Identifiers

PMID: 26401774
DOI: 10.3233/JAD-150214
PMCID: PMC4955593

Genes

PSEN1

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