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Article

Increased functional brain response during word retrieval in cognitively intact older adults at genetic risk for Alzheimer's disease.

NeuroImage - 1 Jul 2010

Wierenga Christina E, Stricker Nikki H, McCauley Ashley, Simmons Alan, Jak Amy J, Chang Yu-Ling, Delano-Wood Lisa, Bangen Katherine J, Salmon David P, Bondi Mark W

Abstract excerpt

Recent language studies in aging and dementia provide two complementary lines of evidence that: (1) measures of semantic knowledge and word-finding ability show declines comparable to those of episodic memory, and greater impairment than executive function measures, during the prodromal period of Alzheimer's disease and (2) cognitively intact older adult carriers of the apolipoprotein E (APOE) epsilon4 allele...

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Source

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Identifiers

PMID: 20298792
DOI: 10.1016/j.neuroimage.2010.03.021
PMCID: PMC2862794

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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