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Article

Menin links the stress response to genome stability in Drosophila melanogaster.

PloS one - 18 Nov 2010

Papaconstantinou Maria, Pepper Alicia N, Wu Ying, Kasimer Dahlia, Westwood Tim, Campos Ana Regina, Bédard Pierre-André

Abstract excerpt

BACKGROUND: The multiple endocrine neoplasia type I gene functions as a tumor suppressor gene in humans and mouse models. In Drosophila melanogaster, mutants of the menin gene (Mnn1) are hypersensitive to mutagens or gamma irradiation and have profound defects in the response to several stresses including heat shock, hypoxia, hyperosmolarity and oxidative stress. However, it is not known if the function of menin...

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Source

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Identifiers

PMID: 21124979
DOI: 10.1371/journal.pone.0014049
PMCID: PMC2987805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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