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Article

Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model.

DNA repair - 6 Aug 2009

Kottemann Molly C, Bale Allen E

Abstract excerpt

MEN1, the gene responsible for the cancer predisposition syndrome multiple endocrine neoplasia type I, has been implicated in DNA repair, cell cycle control, and transcriptional regulation. It is unclear to what degree these processes are integrated into a single encompassing function in normal cellular physiology and how deficiency of the MEN1-encoded protein, "menin", contributes to cancer pathogenesis. In this...

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Source

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Identifiers

PMID: 19608464
DOI: 10.1016/j.dnarep.2009.06.001
PMCID: PMC2745199

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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