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Article

High incidence of mammary intraepithelial neoplasia development in Men1-disrupted murine mammary glands.

The Journal of pathology - 1 Mar 2013

Seigne Christelle, Auret Magdalena, Treilleux Isabelle, Bonnavion Rémy, Assade Fouzia, Carreira Christine, Goddard-Léon Sophie, Lavergne Emilie, Chabaud Sylvie, Garcia Amandine, Mazoyer Sylvie, Lu Jieli, Bachelot Thomas, Frappart Lucien, Zhang Chang Xian

Abstract excerpt

Mutations of the MEN1 tumour suppressor gene predispose patients to the development of multiple endocrine neoplasia type 1 (MEN1) syndrome, which is characterized by multiple endocrine tumours, including prolactinomas. The recent findings of the interaction between menin, encoded by the MEN1 gene, and the oestrogen receptor, as well as the observation of rare cases of mammary carcinomas in our heterozygous Men1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23180448
DOI: 10.1002/path.4146

Genes

MEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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