Article
Lec9 CHO glycosylation mutants are defective in the synthesis of dolichol.
Journal of lipid research - 1 Mar 1990
Rosenwald A G, Krag S S
Abstract excerpt
Lec9 Chinese hamster ovary cells were found previously to be defective in the synthesis of N-linked glycans. This appeared to be the result of a defect in the synthesis of oligosaccharide lipid and lipid phosphate (Rosenwald, Stanley, and Krag. 1989. Mol. Cell. Biol. 9: 914-924). In this study we analyzed the steady state levels of long-chain polyisoprenyl lipids in Lec9 cells. We found that Lec9 cells are...
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