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Article

CHO cells provide access to novel N-glycans and developmentally regulated glycosyltransferases.

Glycobiology - 1 Oct 1996

Stanley P, Raju T S, Bhaumik M

Abstract excerpt

Chinese hamster ovary (CHO) cells express only a subset of the glycosyltransferases activities known to exist. They do not express several fucosyltransferases, galactosyltransferases, sialyltransferases or N-acetylglucosaminyltransferases. However, following mutagenesis or transfection with large amounts of DNA, rare mutants that express a transferase activity de novo have been obtained. The first CHO mutant of...

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PMID: 8953280
DOI: 10.1093/glycob/6.7.695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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CHO cells provide access to novel N-glycans and developmentally regulated glycosyltransferases.PMID 8953280Read ↗

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Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity.Semantic proximity Read ↗

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alpha(1,3)fucosyltransferases expressed by the gain-of-function Chinese hamster ovary glycosylation mutants LEC12, LEC29, and LEC30.Semantic proximity Read ↗

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Five Lec1 CHO cell mutants have distinct Mgat1 gene mutations that encode truncated N-acetylglucosaminyltransferase I.Semantic proximity Read ↗

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