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Article

Mannolipid donor specificity of glycosylphosphatidylinositol mannosyltransferase-I (GPIMT-I) determined with an assay system utilizing mutant CHO-K1 cells.

Glycobiology - 1 Dec 1994

DeLuca A W, Rush J S, Lehrman M A, Waechter C J

Abstract excerpt

The microsomal enzyme glycosylphosphatidylinositol mannosyltransferase I (GPIMT-I) catalyses the transfer of a mannosyl residue from beta-mannosylphosphoryldolichol (beta-Man-P-Dol) to glucosamine-alpha(1,6)(acyl)phosphatidylinositol (GlcN-aPI) to form Man alpha(1,4)GlcN-aPI (ManGlcN-aPI), an intermediate in glycosylphosphatidylinositol (GPI) synthesis. While the transfer of [3H]mannosyl units to endogenous...

Topics

Animals
Biological Assay
CHO Cells
Carbohydrate Sequence
Cricetinae
Glycolipids
Mannose
Mannosyltransferases
Microsomes
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polyisoprenyl Phosphate Sugars

Stereoisomerism

Substrate Specificity

Source

Identifiers

PMID: 7734853
DOI: 10.1093/glycob/4.6.909

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7734853-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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