Article
Regulation of glycosylation. Three enzymes compete for a common pool of dolichyl phosphate in vivo.
The Journal of biological chemistry - 25 Aug 1990
Rosenwald A G, Stoll J, Krag S S
Abstract excerpt
We examined changes in the levels of the dolichol forms in Chinese hamster ovary cells containing alterations in the levels of activity of two enzymes in the oligosaccharyl-P-P-dolichol biosynthetic pathway, namely UDP-GlcNAc:dolichyl phosphate:GlcNAc-phosphotransferase (GlcNAc-1-phosphotransferase) and mannosylphosphoryldolichol (Man-P-Dol) synthase. Under normal conditions in wild type cells,...
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