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Article

A neuropeptide signaling pathway regulates synaptic growth in Drosophila.

The Journal of cell biology - 20 Feb 2012

Chen Xu, Ganetzky Barry

Abstract excerpt

Neuropeptide signaling is integral to many aspects of neural communication, particularly modulation of membrane excitability and synaptic transmission. However, neuropeptides have not been clearly implicated in synaptic growth and development. Here, we demonstrate that cholecystokinin-like receptor (CCKLR) and drosulfakinin (DSK), its predicted ligand, are strong positive growth regulators of the Drosophila...

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Identifiers

PMID: 22331845
DOI: 10.1083/jcb.201109044
PMCID: PMC3283997

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