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Article

Multi-locus test conditional on confirmed effects leads to increased power in genome-wide association studies.

PloS one - 16 Nov 2010

Ma Li, Han Shizhong, Yang Jing, Da Yang

Abstract excerpt

Complex diseases or phenotypes may involve multiple genetic variants and interactions between genetic, environmental and other factors. Current genome-wide association studies (GWAS) mostly used single-locus analysis and had identified genetic effects with multiple confirmations. Such confirmed single-nucleotide polymorphism (SNP) effects were likely to be true genetic effects and ignoring this information in...

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PMID: 21103364
DOI: 10.1371/journal.pone.0015006
PMCID: PMC2982824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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