Article
Multiple testing and power calculations in genetic association studies.
Cold Spring Harbor protocols - 1 Jan 2011
So Hon-Cheong, Sham Pak C
Abstract excerpt
Modern genetic association studies typically involve multiple single-nucleotide polymorphisms (SNPs) and/or multiple genes. With the development of high-throughput genotyping technologies and the reduction in genotyping cost, investigators can now assay up to a million SNPs for direct or indirect association with disease phenotypes. In addition, some studies involve multiple disease or related phenotypes and use...
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