Immune responses in BALB/c mice following immunization with aromatic compound or purine-dependent Salmonella typhimurium strains.

Article

Immune responses in BALB/c mice following immunization with aromatic compound or purine-dependent Salmonella typhimurium strains.

Immunology - 1 Feb 1990

O'Callaghan D, Maskell D, Tite J, Dougan G

Abstract excerpt

Two near isogenic strains of Salmonella typhimurium HWSH, stably mutated in either the aroA gene affecting the biosynthesis of aromatic compounds, or the purA gene affecting the biosynthesis of purines, were administered intravenously as live attenuated vaccines to BALB/c mice. HWSH aroA-immunize...

Topics

Animals
Antibodies, Bacterial
Genes, Bacterial
Immunity, Innate
Immunization
Listeria monocytogenes
Lymphocyte Activation
Male
Mice
Mice, Inbred BALB C
Mutation
Salmonella typhimurium
T-Lymphocytes
Vaccines, Attenuated

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