Article
Comparison of the abilities of different attenuated Salmonella typhimurium strains to elicit humoral immune responses against a heterologous antigen.
Infection and immunity - 1 Feb 1998
Dunstan S J, Simmons C P, Strugnell R A
Abstract excerpt
We compared the abilities of different Salmonella enterica var. Typhimurium (S. typhimurium) strains harboring mutations in the genes aroA, aroAD, purA, ompR, htrA, and cya crp to present the heterologous antigen, C fragment of tetanus toxin, to the mouse immune system. Plasmid pTETtac4, encoding...
Topics
- Animals
- Antibodies, Bacterial
- Bacterial Vaccines
- Female
- Immunization
- Immunoglobulin G
- Interferon-gamma
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Mutation
- Salmonella typhimurium
- Tetanus Toxoid
- Vaccines, Attenuated