Article
Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.
The Journal of biological chemistry - 21 Jan 2011
Stratigopoulos George, LeDuc Charles A, Cremona Maria L, Chung Wendy K, Leibel Rudolph L
Abstract excerpt
The first intron of FTO contains common single nucleotide polymorphisms associated with body weight and adiposity in humans. In an effort to identify the molecular basis for this association, we discovered that FTO and RPGRIP1L (a ciliary gene located in close proximity to the transcriptional sta...
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