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Article

Regulation of Fto/Ftm gene expression in mice and humans.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Apr 2008

Stratigopoulos George, Padilla Stephanie L, LeDuc Charles A, Watson Elizabeth, Hattersley Andrew T, McCarthy Mark I, Zeltser Lori M, Chung Wendy K, Leibel Rudolph L

Abstract excerpt

Two recent, large whole-genome association studies (GWAS) in European populations have associated a approximately 47-kb region that contains part of the FTO gene with high body mass index (BMI). The functions of FTO and adjacent FTM in human biology are not clear. We examined expression of these genes in organs of mice segregating for monogenic obesity mutations, exposed to underfeeding/overfeeding, and to 4...

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Source

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Identifiers

PMID: 18256137
DOI: 10.1152/ajpregu.00839.2007
PMCID: PMC2808712

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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