Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FTO associations with obesity and telomere length.

Journal of biomedical science - 1 Sept 2017

Zhou Yuling, Hambly Brett D, McLachlan Craig S

Abstract excerpt

This review examines the biology of the Fat mass- and obesity-associated gene (FTO), and the implications of genetic association of FTO SNPs with obesity and genetic aging. Notably, we focus on the role of FTO in the regulation of methylation status as possible regulators of weight gain and genetic aging. We present a theoretical review of the FTO gene with a particular emphasis on associations with UCP2, AMPK,...

Topics

Join the communities discussing this publication.

Alpha-Ketoglutarate-Dependent Dioxygenase FTO
FTO gene
UCP2 gene
Obesity
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Telomere Shortening

Source

Open in PubMed Open full text

Identifiers

PMID: 28859657
DOI: 10.1186/s12929-017-0372-6
PMCID: PMC5580219

Genes

FTO
CUX1
IRX3
RBL2
UCP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FTO associations with obesity and telomere length.PMID 28859657Read ↗

The bigger picture of FTO: the first GWAS-identified obesity gene.Semantic proximity Read ↗

The composite alliance of FTO locus with obesity-related genetic variants.Semantic proximity Read ↗

The genetics of obesity: FTO leads the way.Semantic proximity Read ↗

FTO and obesity: a problem for a billion people.Semantic proximity Read ↗

The 'Fat Mass and Obesity Related' (FTO) gene: Mechanisms of Impact on Obesity and Energy Balance.Semantic proximity Read ↗

Complex Relationship between Obesity and the Fat Mass and Obesity Locus.Semantic proximity Read ↗

The role of the FTO (Fat Mass and Obesity Related) locus in regulating body size and composition.Semantic proximity Read ↗

FTO as an epigenetic regulator in metabolic and inflammatory diseasesSemantic proximity Read ↗

Obesity-associated variants within FTO form long-range functional connections with IRX3.Semantic proximity Read ↗

Obesity and FTO: Changing Focus at a Complex Locus.Semantic proximity Read ↗

FTO Gene Affects Obesity and Breast Cancer Through Similar Mechanisms: A New Insight into the Molecular Therapeutic TargetsSemantic proximity Read ↗

Role of FTO in Adipocyte Development and Function: Recent InsightsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.