Article
Activation of the DNA damage checkpoint in yeast lacking the histone chaperone anti-silencing function 1.
Molecular and cellular biology - 1 Dec 2004
Ramey Christopher Josh, Howar Susan, Adkins Melissa, Linger Jeffrey, Spicer Judson, Tyler Jessica K
Abstract excerpt
The packaging of the eukaryotic genome into chromatin is likely to be important for the maintenance of genomic integrity. Chromatin structures are assembled onto newly synthesized DNA by the action of chromatin assembly factors, including anti-silencing function 1 (ASF1). To investigate the role of chromatin structure in the maintenance of genomic integrity, we examined budding yeast lacking the histone chaperone...
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