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Article

Activated cAMP receptors switch encystation into sporulation.

Proceedings of the National Academy of Sciences of the United States of America - 28 Apr 2009

Kawabe Yoshinori, Morio Takahiro, James John L, Prescott Alan R, Tanaka Yoshimasa, Schaap Pauline

Abstract excerpt

Metazoan embryogenesis is controlled by a limited number of signaling modules that are used repetitively at successive developmental stages. The development of social amoebas shows similar reiterated use of cAMP-mediated signaling. In the model Dictyostelium discoideum, secreted cAMP acting on 4 cAMP receptors (cARs1-4) coordinates cell movement during aggregation and fruiting body formation, and induces the...

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Identifiers

PMID: 19369200
DOI: 10.1073/pnas.0901617106
PMCID: PMC2678454

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Source receipt: pubmed, retrieved 7 Sept 2026.

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