Article
Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
Journal of virology - 1 Dec 2010
Weidner Jessica M, Jiang Dong, Pan Xiao-Ben, Chang Jinhong, Block Timothy M, Guo Ju-Tao
Abstract excerpt
Tetherin and IFITM3 are recently identified interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses, respectively. In our efforts to further explore their antiviral activities against other viruses and determine their antiviral mechanisms, we found that the two antiviral proteins potently inhibit the infection of vesicular stomatitis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
