Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tetherin antagonism by SARS‐CoV‐2 ORF3a and spike protein enhances virus release

11 Oct 2023

Abstract excerpt

The antiviral restriction factor, tetherin, blocks the release of several different families of enveloped viruses, including the Coronaviridae. Tetherin is an interferon-induced protein that forms parallel homodimers between the host cell and viral particles, linking viruses to the surface of infected cells and inhibiting their release. We demonstrate that SARS-CoV-2 infection causes tetherin downregulation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to SARS-CoV-2 detection and testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37818801
DOI: 10.15252/embr.202357224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tetherin antagonism by SARS‐CoV‐2 ORF3a and spike protein enhances virus releasePMID 37818801Read ↗

Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral AntagonistsSemantic proximity Read ↗

Tetherin restricts SARS-CoV-2 replication despite antagonistic effects of Spike and ORF7aSemantic proximity Read ↗

Mutations accumulated in the Spike of SARS-CoV-2 Omicron allow for more efficient counteraction of the restriction factor BST2/Tetherin.Semantic proximity Read ↗

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and CounteractionSemantic proximity Read ↗

Severe acute respiratory syndrome coronavirus spike protein counteracts BST2‐mediated restriction of virus‐like particle releaseSemantic proximity Read ↗

Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.Semantic proximity Read ↗

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by TetherinSemantic proximity Read ↗

BST2/Tetherin Inhibition of Alphavirus ExitSemantic proximity Read ↗

Tetherin and Its Viral AntagonistsSemantic proximity Read ↗

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff ActivitySemantic proximity Read ↗

Functional Landscape of SARS-CoV-2 Cellular RestrictionSemantic proximity Read ↗

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.