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Article

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin

27 Nov 2008

Abstract excerpt

The expression of many putative antiviral genes is upregulated when cells encounter type I interferon (IFN), but the actual mechanisms by which many IFN-induced gene products inhibit virus replication are poorly understood. A recently identified IFN-induced antiretroviral protein, termed tetherin (previously known as BST-2 or CD317), blocks the release of nascent human immunodeficiency virus type 1 (HIV-1)...

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Identifiers

PMID: 19036818
DOI: 10.1128/jvi.02211-08

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Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by TetherinPMID 19036818Read ↗

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