Article
Interferon-inducible Transmembrane Protein 3 (IFITM3) Restricts Reovirus Cell Entry
7 May 2013
Abstract excerpt
Reoviruses are double-stranded RNA viruses that infect the mammalian respiratory and gastrointestinal tract. Reovirus infection elicits production of type I interferons (IFNs), which trigger antiviral pathways through the induction of interferon-stimulated genes (ISGs). Although hundreds of ISGs have been identified, the functions of many of these genes are unknown. The interferon-inducible transmembrane (IFITM)...
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