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Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction

6 May 2011

Abstract excerpt

Tetherin (BST2/CD317) has been recently recognized as a potent interferon-induced antiviral molecule that inhibits the release of diverse mammalian enveloped virus particles from infected cells. By targeting an immutable structure common to all these viruses, the virion membrane, evasion of this antiviral mechanism has necessitated the development of specific countermeasures that directly inhibit tetherin...

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PMID: 21994744
DOI: 10.3390/v3050520

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