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Article

ForC lacks canonical formin activity but bundles actin filaments and is required for multicellular development of Dictyostelium cells.

European journal of cell biology - 1 Jan 2000

Junemann Alexander, Winterhoff Moritz, Nordholz Benjamin, Rottner Klemens, Eichinger Ludwig, Gräf Ralph, Faix Jan

Abstract excerpt

Diaphanous-related formins (DRFs) drive the nucleation and elongation of linear actin filaments downstream of Rho GTPase signalling pathways. Dictyostelium formin C (ForC) resembles a DRF, except that it lacks a genuine formin homology domain 1 (FH1), raising the questions whether or not ForC can nucleate and elongate actin filaments. We found that a recombinant ForC-FH2 fragment does not nucleate actin...

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PMID: 23906540
DOI: 10.1016/j.ejcb.2013.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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