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Article

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles.

Genome biology - 1 Jan 2005

Wilkins Andrew, Szafranski Karol, Fraser Derek J, Bakthavatsalam Deenadayalan, Müller Rolf, Fisher Paul R, Glöckner Gernot, Eichinger Ludwig, Noegel Angelika A, Insall Robert H

Abstract excerpt

BACKGROUND: Dictyostelium discoideum is a eukaryote with a simple lifestyle and a relatively small genome whose sequence has been fully determined. It is widely used for studies on cell signaling, movement and multicellular development. Ras guanine-nucleotide exchange factors (RasGEFs) are the proteins that activate Ras and thus lie near the top of many signaling pathways. They are particularly important for...

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Identifiers

PMID: 16086850
DOI: 10.1186/gb-2005-6-8-r68
PMCID: PMC1273635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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