Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stiffness of the substrate influences the phenotype of embryonic chicken cardiac myocytes.

Journal of biomedical materials research. Part A - 15 Dec 2010

Bajaj Piyush, Tang Xin, Saif Taher A, Bashir Rashid

Abstract excerpt

We examined the effect of substrate stiffness on the beating rate, force of contraction, and cytoskeletal structure of embryonic chicken cardiac myocytes by culturing them on laminin-coated polyacrylamide (PA) substrates. Cells cultured on PA substrates with elasticity comparable to that of the native myocardium (18 kPa) exhibited the highest beating rate during the first few days of culture. The initial beating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Chick Embryo
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescence

Share to Focal Adhesions

Share to Myocardial Contraction

Share to Myocytes, Cardiac

Share to Vinculin

Source

Identifiers

PMID: 20939058
DOI: 10.1002/jbm.a.32951

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stiffness of the substrate influences the phenotype of embryonic chicken cardiac myocytes.PMID 20939058Read ↗

Influence of substrate stiffness on the phenotype of heart cells.Semantic proximity Read ↗

Cardiac myocytes respond differentially and synergistically to matrix stiffness and topographySemantic proximity Read ↗

Substrate stiffness modulates gene expression and phenotype in neonatal cardiomyocytes in vitro.Semantic proximity Read ↗

Effects of Substrate Mechanics on Contractility of Cardiomyocytes Generated from Human Pluripotent Stem CellsSemantic proximity Read ↗

3D matrix stiffness modulation unveils cardiac fibroblast phenotypic switching.Semantic proximity Read ↗

Regulation of Cardiomyocyte Adhesion and Mechanosignalling Through Distinct Nanoscale Behaviour of Integrin Ligands Mimicking Healthy or Fibrotic ECMSemantic proximity Read ↗

Construction of cell-containing, anisotropic, three-dimensional collagen fibril scaffolds using external vibration and their influence on smooth muscle cell phenotype modulation.Semantic proximity Read ↗

Contractility of cardiac and skeletal muscle tissue increases with environmental stiffnessSemantic proximity Read ↗

Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatternsSemantic proximity Read ↗

Focal adhesion kinase regulates early steps of myofibrillogenesis in cardiomyocytesSemantic proximity Read ↗

Intercellular adhesion stiffness moderates cell decoupling on stiff substratesSemantic proximity Read ↗

Engineering Shape-Controlled Microtissues on Compliant Hydrogels with Tunable Rigidity and Extracellular Matrix Ligands.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.