Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering Shape-Controlled Microtissues on Compliant Hydrogels with Tunable Rigidity and Extracellular Matrix Ligands.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Rexius-Hall Megan L, Ariyasinghe Nethika R, McCain Megan L

Abstract excerpt

In vitro models that recapitulate key aspects of native tissue architecture and the physical microenvironment are emerging systems for modeling development and disease. For example, the myocardium consists of layers of aligned and coupled cardiac myocytes that are interspersed with supporting cells and embedded in a compliant extracellular matrix (ECM). These cell-cell and cell-matrix interactions are known to be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Communication
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Microenvironment

Share to Elastic Modulus

Share to Hydrogels

Share to Myocytes, Cardiac

Share to Surface Properties

Share to Tissue Engineering

Source

Identifiers

PMID: 33340354
DOI: 10.1007/978-1-0716-1174-6_5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering Shape-Controlled Microtissues on Compliant Hydrogels with Tunable Rigidity and Extracellular Matrix Ligands.PMID 33340354Read ↗

Cardiac myocytes respond differentially and synergistically to matrix stiffness and topographySemantic proximity Read ↗

Leveraging microtopography to pattern multi-oriented muscle actuatorsSemantic proximity Read ↗

Engineering aligned human cardiac muscle using developmentally inspired fibronectin micropatternsSemantic proximity Read ↗

The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices.Semantic proximity Read ↗

Mechanical stretch sustains myofibroblast phenotype and function in microtissues through latent TGF-β1 activation.Semantic proximity Read ↗

Multiplexing physical stimulation on single human induced pluripotent stem cell-derived cardiomyocytes for phenotype modulation.Semantic proximity Read ↗

Effects of Substrate Mechanics on Contractility of Cardiomyocytes Generated from Human Pluripotent Stem CellsSemantic proximity Read ↗

I-Wire Heart-on-a-Chip I: Three-dimensional cardiac tissue constructs for physiology and pharmacology.Semantic proximity Read ↗

Regulation of Cardiomyocyte Adhesion and Mechanosignalling Through Distinct Nanoscale Behaviour of Integrin Ligands Mimicking Healthy or Fibrotic ECMSemantic proximity Read ↗

3D Cardiac Microtissues Encapsulated with the Co‐Culture of Cardiomyocytes and Cardiac FibroblastsSemantic proximity Read ↗

Microfluidically Aligned Collagen to Maintain the Phenotype of Tenocytes In Vitro.Semantic proximity Read ↗

The development of a platform to manipulate cardiomyocyte structure and functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.