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Effects of Substrate Mechanics on Contractility of Cardiomyocytes Generated from Human Pluripotent Stem Cells

1 Jan 2012

Abstract excerpt

Human pluripotent stem cell (hPSC-) derived cardiomyocytes have potential applications in drug discovery, toxicity testing, developmental studies, and regenerative medicine. Before these cells can be reliably utilized, characterization of their functionality is required to establish their similarity to native cardiomyocytes. We tracked fluorescent beads embedded in 4.4-99.7 kPa polyacrylamide hydrogels beneath...

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3D Printing in Biomedical Research
Pluripotent Stem Cells Research
Tissue Engineering and Regenerative Medicine

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22649451
DOI: 10.1155/2012/508294

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