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Article

Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.

BMC cancer - 8 Oct 2010

Becks Lisa, Prince Misty, Burson Hannah, Christophe Christopher, Broadway Mason, Itoh Ken, Yamamoto Masayuki, Mathis Michael, Orchard Elysse, Shi Runhua, McLarty Jerry, Pruitt Kevin, Zhang Songlin, Kleiner-Hancock Heather E

Abstract excerpt

BACKGROUND: Activation of nuclear factor erythroid 2-related factor (Nrf2), which belongs to the basic leucine zipper transcription factor family, is a strategy for cancer chemopreventive phytochemicals. It is an important regulator of genes induced by oxidative stress, such as glutathione S-transferases, heme oxygenase-1 and peroxiredoxin 1, by activating the antioxidant response element (ARE). We hypothesized...

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Identifiers

PMID: 20932318
DOI: 10.1186/1471-2407-10-540
PMCID: PMC2964634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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