Mechanism-Based Cancer Prevention Approaches: Targets, Examples, and the Use of Transgenic Mice

Abstract excerpt

Humans are exposed to a wide variety of carcinogenic insults, including endogenous and man-made chemicals, radiation, physical agents, and viruses. The ultimate goal of carcinogenesis research is to elucidate the processes involved in the induction of human cancer so that interventions may be developed to prevent the disease, either in the general population or in susceptible subpopulations. Progress to date in...

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