Article
The involvement of NRF2 in lung cancer.
Oxidative medicine and cellular longevity - 1 Jan 2013
Bauer Alison K, Hill Thomas, Alexander Carla-Maria
Abstract excerpt
Nuclear factor, erythroid-derived 2, like 2 (NRF2) is a key regulator of antioxidants and cellular stress responses. The role of NRF2 in pulmonary neoplasia, a diverse disease for which few biomarkers exist, is complicated and appears to depend on several main factors including the existence of activating mutations in NRF2 and/or loss of function mutations in KEAP1 and the stage of carcinogenesis studied,...
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