Article
LRP receptor family member associated bone disease.
Reviews in endocrine & metabolic disorders - 1 Jun 2015
Lara-Castillo N, Johnson M L
Abstract excerpt
A dozen years ago the identification of causal mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene involved in two rare bone disorders propelled research in the bone field in totally new directions. Since then, there have been an explosion in the number of reports that highlight the role of the Wnt/β-catenin pathway in the regulation of bone homeostasis. In this review we discuss some...
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