Associations of LRP5 Gene With Bone Mineral Density, Bone Turnover Markers, and Fractures in the Elderly With Osteoporosis.

doi:10.3389/fendo.2020.571549

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Article

Associations of LRP5 Gene With Bone Mineral Density, Bone Turnover Markers, and Fractures in the Elderly With Osteoporosis.

Frontiers in endocrinology - 1 Jan 2020

Wang Qi-Fei, Bi Hong-Sen, Qin Ze-Lian, Wang Pu, Nie Fang-Fei, Zhang Guang-Wu

Abstract excerpt

Objective: The study aimed to explore the associations of rs4988300 and rs634008 in the low-density lipoprotein receptor-related protein 5 (LRP5) gene with bone mineral density (BMD), bone turnover markers (BTM), and fractures in elderly patients with osteoporosis (OP). Methods: Our study included 328 unrelated OP patients with or without fractures. Genomic DNA was extracted for genotyping. BTM levels were...

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PMID: 33101205
DOI: 10.3389/fendo.2020.571549
PMCID: PMC7545741

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