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Article

Decreased Neuregulin 1 C-terminal fragment in Brodmann's area 6 of patients with schizophrenia.

Schizophrenia research - 1 Dec 2010

Barakat Adel, Dean Brian, Scarr Elizabeth, Evin Geneviève

Abstract excerpt

Neuregulin 1 (NRG1) is a susceptibility gene for schizophrenia. A decrease in NRG1-ErbB4 signalling has also been associated with the disease. β-amyloid precursor protein-cleaving enzyme (BACE1) processes type III NRG1 precursor, a major neuregulin variant expressed in the brain, to release NRG1...

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Source

Identifiers

PMID: 20926259
DOI: 10.1016/j.schres.2010.09.001

Genes

NRG1
BACE1
CHRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20926259-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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